scholarly journals Interphase karyotypic analysis of chromosomes 11, 17 and X in invasive squamous-cell carcinoma of the cervix: Morphological correlation with HPV infection

Author(s):  
Shirley A. Southern ◽  
C. Simon Herrington
2020 ◽  
pp. 1-4
Author(s):  
Judith Dominguez-Cherit

<b><i>Introduction:</i></b> Subungual squamous cell carcinoma (sSCC) is the most frequent malignant tumor of the nail unit. When suspecting sSCC, accurate diagnosis is supported by nail biopsy. Depth of invasion and histopathologic signs of human papillomavirus (HPV) infection are related to an unfavorable prognosis. In this case, it is necessary to rule out bone invasion by radiography or MRI, and in case of doubt, amputation is indicated. <b><i>Case Presentation:</i></b> We present 2 cases of sSCC with a confirmatory biopsy of sSCC with HPV and invasion; in both cases, MRI was difficult to distinguish between bone invasion and bone marrow inflammation. Before amputating the distal phalanx, we decided to perform a bone biopsy during the excisional surgery. Neither case required amputation. <b><i>Conclusion:</i></b> We propose that when an invasive sSCC is present and an MRI is doubtful of bone invasion, before amputating, a bone biopsy should be performed.


2019 ◽  
Vol 45 (2) ◽  
pp. e85
Author(s):  
L. Bognar ◽  
S. Bellyei ◽  
I. Hegedus ◽  
K. Gombos ◽  
O.P. Horvath ◽  
...  

2015 ◽  
Vol 105 (4) ◽  
pp. 374-376
Author(s):  
Morteza Khaladj ◽  
Rose-Mary Mbibong ◽  
Nisha Shah ◽  
Ayesha Mohiuddin ◽  
Aqsa Siddiqui

Squamous cell carcinomas are often seen on the sun-exposed areas of the skin and are rarely observed on the digits of the foot. However, there have been incidences of squamous cell carcinoma developing in the presence of chronic wounds with osteomyelitis, thus complicating the treatment. We present a patient with osteomyelitis who developed invasive squamous cell carcinoma of the third digit. We conclude that wounds with osteomyelitis may have underlying pathologic abnormalities that are not obvious on initial presentation.


2014 ◽  
Vol 9 (1) ◽  
pp. 7 ◽  
Author(s):  
Anthony Mwololo ◽  
Joshua Nyagol ◽  
Emily Rogena ◽  
Willis Ochuk ◽  
Mary Kimani ◽  
...  

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